Pierre-Alexandre Gagnon

3rd cycle student member

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ)

Médecine

2725 Chemin Sainte-Foy

, Québec

(Québec)

G1V 4G5

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Areas of research

  • Asthme
  • Cellules structurales bronchiques
  • Inflammation
  • Remodelage
  • Thermoplastie bronchique

University

Université Laval

Primary axis of the AIRS Network

Omics and biological determinants of health

Secondary axis(s)

Care, prevention and health promotion

Research sectors

  • Health

Research types

  • Fundamental
  • Translational

Diplomas

  • B.Sc
  • M.Sc

Research work

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NAME OF DIRECTOR:

Jamila Chakir (directrice), Andréanne Côté (co-directrice)

Bibliographic references and DOIs

Klein M, Gagnon PA, Salem M, Rouabhia M, Chakir J. MicroRNA-155-5p Differentially Regulates IL-13Rα1 and IL-13Rα2 Expression and Signaling Driving Abnormal Lung Epithelial Cell Phenotype in Severe Asthma. Am J Respir Cell Mol Biol. 2024 Nov;71(5):603-616. doi: 10.1165/rcmb.2024-0089OC.

Gagnon PA, Klein M, De Vos J, Biardel S, Côté A, Godbout K, Laviolette M, Laprise C, Assou S, Chakir J. S100A alarmins and thymic stromal lymphopoietin (TSLP) regulation in severe asthma following bronchial thermoplasty. Respir Res. 2023 Nov 23;24(1):294. doi: 10.1186/s12931-023-02604-1.

Gagnon PA, Côté A, Klein M, Biardel S, Laviolette M, Godbout K, Bossé Y, Chakir J. The reduction of airway smooth muscle by bronchial thermoplasty stands the test of time. ERJ Open Res. 2023 Jul 3;9(4):00024-2023. doi: 10.1183/23120541.00024-2023.

Chakir J, Gagnon PA, Laviolette M. Bronchial thermoplasty: The heat that reprograms the airways? J Allergy Clin Immunol. 2021 Nov;148(5):1167-1169. doi: 10.1016/j.jaci.2021.09.004. Epub 2021 Sep 9. PMID: 34509527.

Vernet R, Matran R, Zerimech F, Madore AM, Lavoie ME, Gagnon PA, Mohamdi H, Margaritte-Jeannin P, Siroux V, Dizier MH, Demenais F, Laprise C, Nadif R, Bouzigon E. Identification of novel genes influencing eosinophil-specific protein levels in asthma families. J Allergy Clin Immunol. 2022 Nov;150(5):1168-1177. doi: 10.1016/j.jaci.2022.05.017.