Andres Bruno Rojas Ruiz

3rd cycle student member

Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval.

Faculté de Médecine

2725 Chemin Ste-Foy, Québec, QC

, Quebec

(Québec)

G1V 4G5

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Areas of research

  • Hypoxie chronique
  • Maladies respiratoires
  • Adaptation à la haute altitude
  • Asthme
  • Mécanique respiratoire

University

Université Laval

Primary axis of the AIRS Network

Environmental quality measurements

Secondary axis(s)

Environmental quality measurements

Research sectors

  • Health

Research types

  • Fundamental

Diplomas

  • B.Sc
  • M.Sc

Research work

My research examines the impact of hypoxia on lung function, with particular emphasis on respiratory mechanics in a murine model of allergic asthma. BALB/c mice are exposed to fixed periods of normobaric hypoxia to evaluate alterations in respiratory mechanics, allergic inflammation, and airway responsiveness. The primary objective is to determi...

NAME OF DIRECTOR:

Ynuk Bossé

ORCID NUMBER:

0000-0002-3780-4278

Bibliographic references and DOIs

Rojas-Ruiz, A., Boucher, M., Henry, C., Gélinas, L., Packwood, R., Graham, P., Soliz, J., & Bossé, Y. (2025). Methacholine hyperresponsiveness in mice with house dust mite-induced lung inflammation is not associated with excessive airway constriction ex vivo. Experimental Physiology, 1–13. https://doi.org/10.1113/EP092522

Boucher M., Henry C., Gélinas L., Packwood R., Rojas-Ruiz Andrés, Fereydoonzad L., Graham P. & Bossé, Y. High throughput screening of airway constriction in mouse lung slices. Scientific Reports 14, 20133 (2024). https://doi.org/10.1038/s41598-024-71170-3

Rojas-Ruiz, A., Boucher, M., Henry, C. et al. Lung Volumes in a Mouse Model of Pulmonary Allergic Inflammation. Lung 202, 637–647 (2024). https://doi.org/10.1007/s00408-024-00730-1

Rojas-Ruiz A., Boucher M., Gill R., Gélinas L., Tom F.Q., Fereydoonzad L., Graham P., Soliz J. & Bossé Y. Lung stiffness of C57BL/6 versus BALB/c mice. Scientific Reports 13, 17481 (2023). https://doi.org/10.1038/s41598-023-44797-x

Boucher M., Dufour-Mailhot A., Tremblay-Pitre S., Khadangi F., Rojas-Ruiz A, Henry C. & Bossé, Y. In mice of both sexes, repeated contractions of smooth muscle in vivo greatly enhance the response of peripheral airways to methacholine. Respiratory Physiology & Neurobiology. 304:103938 (2022) https://doi.org/10.1016/j.resp.2022.103938